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M. Meckel, V. Kubíček, P. Hermann, M. Miederer, F. Rösch.
A DOTA based bisphosphonate with an albumin binding moiety for delayed body clearance for bone targeting.
Nucl Med Biol. 2016 Nov;43(11):670-678. doi:
10.1016/j.nucmedbio.2016.07.009.
M. Perez-Malo, E. Eppard, F. Rösch.
Improves efficacy of synthesis ofM(III)-labeled radiopharmaceuticals in mixtures of aqueous solution and non-aqueous solvents Angewante
A. De la Fuente, E. Eppard, N. Mohr, M. Allmeroth, R. Zentel, F. Rösch.
Labeling of HPMA-based polymer conjugates with metallic radionuclides for theranostic applications (2016)
T. Fritz T, M. Voigt, M. Worm, I. Negwer, S. Müller, K. Kettenbach, T. Ross, F. Rösch, K. Koynov, H. Frey, M. Helm.
Orthogonal click conjugation to the liposomal surface reveals stability of lipid anchorage as crucial for targeting (2016)
E. Eppard, M. Perez-Malo, F. Rösch.
Improved radiolabeling of DOTATOC with trivalent radiometals for clinical application by addition of ethanol
EJNMMI Radiopharmacy and Chemistry 2016 1:6
DOI: 10.1186/s41181-016-0010-8
M. Meckel, A. Nauth, J. Timpe, K. Zhernosekov, A.D. Puranik, R.P. Baum, F. Rösch.
Development of a [(177)Lu]BPAMD Labeling Kit and an Automated Synthesis Module for Routine Bone Targeted Endoradiotherapy.
Cancer Biother Radiopharm. 2015 Mar;30(2):94-9. doi: 10.1089
T.D. Poeppel, C. Boy, A. Bockisch, J. Kotzerke, I. Buchmann, S. Ezziddin, K. Scheidhauer, B.J. Krause, D. Schmidt,
H. Amthauer, F. Rösch, J. Nagarajah, D. Führer, H. Lahner, G. Pöpperl, D. Hörsch, M.A. Walter, R.P. Baum.
Peptide receptor radionuclide therapy for patients with somatostatin receptor expressing tumours.
German Guideline (S1).
Nuklearmedizin. 2015 Feb 16;54(1):1-11.
J.N. Cremer, K. Amunts, J.Graw, M. Piel, F. Rösch, K. Zilles.
Neurotransmitter receptor density changes in Pitx3ak mice--a model relevant to Parkinson's disease.
Neuroscience. 2015 Jan 29;285:11-23. doi: 10.1016
A. Habermeier, J. Graf, B.F. Sandhöfer, J.P. Boissel, F. Rösch, E.I. Closs.
System L amino acid transporter LAT1 accumulates O-(2-fluoroethyl)-L-tyrosine (FET).
Amino Acids February 2015, Volume 47, Issue 2, pp 335-344
V. Radchenko, S. Busse, F. Rösch.
Desferrioxamine as an appropriate chelator for 90Nb: comparison of its complexation properties for M-Df-Octreotide (M = Nb, Fe, Ga, Zr).
Nucl Med Biol. 2014 Oct;41(9):721-7. doi: 10.1016/j.nucmedbio.2014.06.006. Epub 2014 Jul 4.
M. Piel, I. Vernaleken, F. Rösch.
Positron Emission Tomography in CNS Drug Discovery and Drug Monitoring
J. Med. Chem. 2014, 57, 9232−9258
dx.doi.org / 10.1021 / jm5001858
E. Eppard, M. Wuttke, P.L. Nicodemus, F. Rösch
Ethanol-Based Post-processing of Generator-Derived 68Ga Toward Kit-Type Preparation of 68Ga-Radiopharmaceuticals.
J Nucl Med. 2014 Apr 21. [Epub ahead of print]
E. Eppard, N.S. Loktionova, F. Rösch
Quantitative online isolation of 68Ge from 68Ge/68Ga generator eluates for purification and immediate quality control of breakthrough
Applied Radiation and Isotopes 82 (2013) 45-48
F. Beyerlein, M. Piel, S. Höhnemann, F. Rösch
Automated synthesis and purification of [18F]fluoro-[di-deutero]methyl tosylate
J. Label Compd. Radiopharm 2013, 56 360-363
A.F. Martins, M.I.M. Prata, S.P.J. Rodrigues, C.F.G.C. Geraldes, P.J. Riss, A. Amor-Coarasa, C. Burchardt, C. Kroll,
F. Rösch
Spectroscopic, radiochemical, and theoretical studies of the Ga3+-N-2hydroxyethyl piperazine-N’-2-ethanesulfonic acid (HEPES buffer) system: evidence for the formation of Ga3+- HEPES complexes in 68Ga labelling reactions
Eur J Nucl Med Mol Imaging 2013, 8 265-273
F. Zoller, P.J. Riss, F-P. Montforts, DK. Kelleher, E. Eppard, F. Rösch
Radiolabelling and preliminary evaluation of 68Ga-tetrapyrrole derivatives as potential tracers for PET
Nuclear Medicine and Biology 40 (2013) 280–288
F. Rösch
Past, present and future of 68Ge/68Ga generators.
Appl Radiat Isot. 76 (2013) 24-30
doi:pii: S0969-8043(12)00535-0. 10.1016/j.apradiso.2012.10.012.
F. Rösch
68Ge/68Ga generators and 68Ga radiopharmaceutical chemistry on their way into a new century.
J Postgrad Med, Edu Res 47(19 (2013) 18-25
J.P. Riss, S. Hoehnemann, M. Piel, F. Rösch
Two-step radiosynthesis of [18F]FE-β-CIT and [18F]PR04.MZ
J. Label Compds. Radiopharm 2013, 56 356-359
P.J. Riss, K. Stockhofe, F. Rösch
Tropane derived 11C and 18F-labelled DAT ligands
J Lab. Compds. Radiopharm. 56 (2013) 149-158.
DOI: 10.1002/jclr.3018
B.P. Waldron, D. Parker, C. Burchardt, D.S. Yufit, M. Zimny, F. Rösch
Structure and stability of hexadentate complexes of ligands based on AAZTA for efficient PET labelling with gallium-68.
Chem Commun (Camb). 2013 Jan 21;49(6):579-81.
doi: 10.1039/c2cc37544c. Epub 2012 Dec 4.
E. Koumarianou, N.S. Loktionova, M. Fellner, F. Rösch, O. Thews, D. Pawlak, S.C. Archimandritis, R. Mikolajczak
44Sc-DOTA-BN[2-14]NH(2) in comparison to 68Ga-DOTA-BN[2-14]NH2 in pre-clinical investigation. Is 44Sc a potential radionuclide for PET?
Appl Radiat Isot. 70/12 (2012) 2669-76.
doi: 10.1016/j.apradiso.2012.08.004. Epub 2012 Aug 23.
M. Pruszyński, A. Majkowska-Pili, N.S. Loktionova, E. Eppard, F. Rösch
Radiolabelling of DOTATOC with the long-lived positron emitter 44Sc.
Appl Radiat Isot 70/6 (2012) 974-9.
F. Rösch
Scandium-44 –Benefits of a long-lived PET radioisotope available from the 44Ti/44Sc generator system.
Current Radiopharmaceutical 5 (2012) 187-201
P.J. Riss, C. Burchardt, F. Rösch
A methodical 68Ga-labelling study of DO2A-(butyl-L-tyrosine)2 with cation-exchanger post-processed 68Ga: practical aspects of radiolabelling.
Contrast Media Mol Imaging. 6(6) (2011) 492-8.
V. Radchenko, H. Hauser, M. Eisenhut, Dj. Vugts, G.A.M.S. van Dongen, F. Rösch
90Nb – a potential PET nuclide: production and labeling of monoclonal antibodies
Radiochim Acta 100 (2012) 1–7
M. Fellner, P. Riss, N.S. Loktionova, K.P. Zhernosekov, O. Thews, C.F.G.C. Geraldes, Z. Kovacs, I. Lukes , F. Rösch
Comparison of different phosphorus-containing ligands complexing 68Ga for PET-imaging of bone metabolism
Radiochimica Acta 99/1 (2011) 43-51
V. Kumar, D.K. Boddeti, S.C. Evans, F. Rösch, R. Howman-Giles
Potential use of 68Ga-apo-transferrin as a PET imaging agent for detecting Staphylococcus aureus infection.
Nuclear Medicine and Biology 38 (2011) 393–398
A. Bauman, M. Piel, S. Höhnemann, A. Krauss, M. Jansen, C. Solbach, G. Dannhardt, F. Rösch
Synthesis, labelling and evaluation of hydantoin-substituted indole carboxylic acids as potential ligands for PET-Imaging of the glycine binding site of the NMDA-receptor
J Labell Compds Radiopharm (2011) [Epub ahead of print]
P. J. Riss, C. Burchardt, F. Rösch
A methodical 68Ga-labelling study of DO2A-(butyl-L-tyrosine)2 with cation-exchanger post-processed 68Ga: practical aspects of radiolabelling
Contrast Media Molecular Imaging (2011) [Epub ahead of print]
M. Hemmelmann, C. Knoth, U. Schmitt, M. Allmeroth, D. Moderegger, M. Barz, K. Koynov, C. Hiemke, F. Rösch, R. Zentel
HPMA based amphiphilic copolymers mediate central nervous effects of domperidone.
Macromol Rapid Commun. (2011) Apr 5. doi: 10.1002/marc.201000810.
M. Fellner, W. Dillenburg, H.-G. Buchholz, N. Bausbacher, M. Schreckenberger, F. Renz, F. Rösch, O. Thews
Assessing p-glycoprotein (Pgp) activity in vivo utilizing 68Ga-Schiff base complexes
Mol Imaging Biol. 2010 Sep 8.
M.M. Herth, M. Barz, M. Jahn, R. Zentel, F. Rösch
72/74 As-labeling of HPMA based polymers for long-term in vivo PET imaging
Bioorg Med Chem Lett. 20/18 (2010) 5454-8
P.J. Riss, M. Piel, V. Bockhart, N. Bausbacher, H.-G. Buchholz, H. Lueddens, F. Rösch
The DAT ligand [18F]PR17. MZ mirrors the in vivo pharmacokinetic profile of [11C]cocaine with significantly improved monoamine transporter selectivity
ChemMedChem. 5/10 (2010) 1686-8
P.J. Riss, N. Hanik, F. Rösch
Studies towards the development of lipophilic bifunctional N3S3 chelators for 68Ga.
Radiochimica Acta 98/8 (2010) 519-523
F. Zoller, P.J. Riss, F-P. Montforts, F. Rösch
Efficient post-processing of aqueous generator eluates facilitates 68Ga-labelling under anhydrous conditions
Radiochimica Acta 98/3 (2010) 157-160
V. Kramer, M.M. Herth, M.A. Santini, M. Palner, G.M. Knudsen, F. Rösch
Structural combination of established 5-HT receptor ligands: New aspects of the binding mode
Chem Biol Drug Des. 76(4) (2010) 361-6
F. Rösch, P.J. Riss
The Renaissance of the 68Ge/68Ga radionuclide generator initiates new developments in 68Ga
radiopharmaceutical chemistry
Curr Top Med Chem. 10/16 (2010) 1633-68
E. Hühn, H.-G. Buchholz, G. Shazly, S. Maus, O. Thews, N. Bausbacher, F. Rösch, M. Schreckenberger, P. Langguth
Predicting the in vivo release from a liposomal formulation by IVIVC and non-invasive positron emission tomography imaging
Eur J Pharm Sci. 41/1 (2010) 71-77
O. Thews, W. Dillenburg, M. Fellner, H.-G. Buchholz, N. Bausbacher, M. Schreckenberger, F. Rösch
Activation of P-glycoprotein (Pgp)-mediated drug efflux by extracellular acidosis: in vivo imaging with 68Ga-labelled PET tracer
Eur J Nucl Med Mol Imaging. 37(10) (2010) 1935-42
J. Notni, P. Hermann, J. Havlíčková, J. Kotek, V. Kubíček, J. Plutnar, N. Loktionova, P.J. Riss, F. Rösch, I. Lukeš
A triazacyclononane-based bifunctional phosphinate ligand for the preparation of multimeric 68Ga tracers for Positron Emission Tomography
Chemistry. 16/24 (2010) 7174-85
F. Debus, M.M. Herth, M. Piel, H.-G. Buchholz, N. Bausbacher, V. Kramer, H. Lüddens, F. Rösch
18F-labeling and evaluation of novel MDL 100907 derivatives as potential 5-HT2A antagonists for molecular imaging
Nucl Med Biol. 37(4) (2010) 487-95
F. Rösch
Impurity in 68Ga-peptide preparation using processed generator eluate
J Nucl Med 51 (2010) 496
M. Fellner, R.P. Baum, J.A. Peters, I. Lukeš, P. Hermann, V. Prasad, F. Rösch
PET/CT imaging of osteoblastic bone metastases with 68Ga-bisphosponates - first in human study
Eur J Nucl Med Mol Imaging 37(4) (2010) 834
P.J. Riss, F. Rösch
Effective microwave-assisted direct radiosynthesis of [18F]PR04.MZ, and [18F]LBT999: Selective dopamine transporter ligands for qunatitative molecular imaging by means of PET
Bioorg Med Chem 17(22) (2009) 7630-4
M.M. Herth, V. Kramer, F. Rösch
Synthesis of novel WAY 100635 derivatives containing a norbornene group and radiofluoroination of
[18F]AH1.MZ, as a Serotonin 5-HT1A receptor antagonist for molecular imaging
J Label Compd Radiopharm 52/6 (2009) 201-207
P.J. Riss, V. Soskic, A. Schrattenholz, F. Rösch
Synthesis and radiosynthesis of N5-[18F]fluoroethyl-pirenzepine and its metabolite N5-[18F]fluoroethyl-LS 75
J Label Compd Radiopharm 52 (2009) 576-9
P.J. Riss, F. Debus, R. Hummerich, U. Schmidt, P. Schloss, H. Lueddens, F. Rösch
Ex vivo and in vivo evaluation of [18F]PR04.MZ in rodents: a selective dopamine transporter imaging agent
ChemMedChem 4(9) (2009) 1480-7
P.J. Riss, J.M. Hooker, D. Alexoff, S.W. Kim, J.S. Fowler, F. Rösch
[11C]PR04.MZ, a promising DAT ligand for low concentration imaging: Synthesis, efficient 11C-O-methylation and initial small animal PET studies
Bioorg Med Chem Lett 19(15) (2009) 4343-5
C. Burchardt, P.J. Riss, F. Zoller, S. Maschauer, O. Prante, T. Kuwert, F. Rösch
[68Ga]Ga-DO(2)A-(OBu-l-tyr)(2): Synthesis, 68Ga-radiolabeling and in vitro studies of a novel 68Ga-DO(2)A-tyrosine conjugate as potential tumor tracer for PET
Bioorg Med Chem Lett 19(13) (2009) 3498-501
M.M. Herth, M. Barz, D. Moderegger, M. Allmeroth, M. Jahn, O. Thews, R. Zentel, F. Rösch
Radioactive labeling of defined HPMA-based polymeric structures using [18F]FETos for in vivo imaging by Positron Emission Tomography
Biomacromolecules 10 (2009) 1697-170
M.M. Herth, M. Piel, F. Debus, U. Schmitt, H. Lüddens, F. Rösch
Preliminary in vivo and ex vivo evaluation of the 5-HT2A imaging probe [18F]MH.MZ
Nucl Med Biol 36(4) (2009) 447-54
M.M. Herth, V. Kramer, M. Piel, M. Palner, P.J. Riss, G.M. Knudsen, F. Rösch
Synthesis and in vitro affinities of various MDL 100907 derivatives as potential 18F-radioligands for 5-HT2A receptor imaging with PET
Bioorg Med Chem. 17(8) (2009) 2989-3002
Riss PJ, Rösch F.
A convenient chemo-enzymatic of trans-1-toluenesulfonyloxymethyl-2-fluoromethyl-cyclopropane.
Org Biomol Chem. 6 (2008) 4567–4574.
Riss PJ, Kroll C, Nagel V, Rösch F.
NODAPA-OH and NODAPA-(NCS)n: Synthesis, 68Ga-radiolabelling and in vitro characterisation of novel versatile bifunctional chelators for molecular imaging.
Bioorg Med Chem Let. 18 (2008) 5364–5367.
F. Rösch
Radiochemistry and Radiopharmaceutical Chemistry for Medicine
In: Encyclopedia of Life Support Systems, Eolss Publishers Co Ltd, Oxford , UK, 2008, in press
T. Kienast, T. Siessmeier, J. Wrase, D.F. Braus, MN. Smolka, H.-G. Buchholz, M. Rapp, M. Schreckenberger, F. Rösch,
P. Cumming, G. Gründer, K. Mann, P. Bartenstein, A. Heinz
Ratio of dopamine synthesis capacity to D2 receptor availability in ventral striatum correlates with central processing of affective stimuli
Eur J Nucl Med Mol Imaging. 2008, in press
C. Fehr, I. Yakushev, N. Hohmann, H.-G. Buchholz, C. Landvogt, H. Deckers, A. Eberhardt, M. Kläger, MN. Smolka,
A. Scheurich, T. Dielentheis, L.G. Schmidt, F. Rösch, P. Bartenstein, G. Gründer, M. Schreckenberger
Dependent smoking leads to a decrease in striatal dopamine D2 receptor availability similar to other drugs of abuse
American J Psychiatry, Articles, 2008, accepted
T. Betzel, T. Heß, B. Waser, J.-C. Reubi, F. Rösch
closo-Borane Conjugated Regulatory Peptides Retain High Biological Affinity: Synthesis of closo-Borane Conjugated Tyr3-Octreotate Derivatives for BNCT
Bioconj Chem, 2008, accepted
M. Piel, A. Bauman, R.P. Baum, S. Höhnemann, I. Klette, R. Wortmann, F. Rösch
Improved automated synthesis of [18F]fluoroethylcholine as a radiotracer for cancer imaging
Bioorg Med Chem 15 (2007) 3171-3175
F. Rösch
Radiolanthanides in endoradiotherapy: an overview
Radiochim Acta 95 (2007) 303-311
D. Stark, M. Piel, H. Hübner, P. Gmeiner, G. Gründer, F. Rösch
In vitro affinities of various halogenated benzamide derivatives as potential radioligands for non-invasive quantification of D2-like dopamine receptors
Bioorg Med Chem 15 (2007) 6819-6829
I. Vernaleken, C. Weibrich, T. Siessmeier, H.-G. Buchholz, F. Rösch, A. Heinz, P. Cumming, P. Stoeter, P. Bartenstein,
G. Gründer
Asymmetry in dopamine D2/3 receptors of NC is lost with age
Neuroimmage 34 / 3 (2007) 870-878
C.h. Fehr, I. Yakushev, N. Hohmann, H.-G. Buchholz, Ch. Landvogt, G. Gründer, H. Deckers, A. Eberhardt, M. Kläger,
M. Smolka, A. Scheurich, T. Dielentheis, .LG. Schmidt, F. Rösch, P. Bartenstein, M. Schreckenberger
Dependent smoking leads to a decrease in striatal dopamine D2 receptor availability similar to other drugs of abuse
American Journal of Psychiatry, 2007, in press
T. Siessmeier, T. Kienast, J. Wrase, J.L. Larsen, D.F. Braus, MN. Smolka, H.-G. Buchholz, M. Schreckenberger, F. Rösch, P. Cumming, K. Mann, P. Bartenstein, A. Heinz
Antiamphiphysin-positive stiff-person syndrome associated with small cell lung cancer
Mov Disord. 21 (2006) 1285-1287.
G. Gründer, C. Landvogt, I. Vernaleken, H.-G. Buchholz, J. Ondracek, T. Siessmeier, S. Hartter, M. Schreckenberger,
P. Stoeter, C. Hiemke, F. Rösch, DF. Wong, P. Bartenstein
The striatal and extrastriatal D2/D3 receptor-binding profile of clozapine in patients with schizophrenia
Neuropsychopharmacology 31(5) (2006) 1027-35
I. Vernaleken, T. Siessmeier, H.-G. Buchholz, S. Härtter, C. Hiemke, P. Stoeter, F. Rösch, P. Bartenstein, G. Gründer
High striatal occupancy of D2-like dopamine receptors by amisulpride in the brain of patients with schizophrenia
Int J Neuropsychopharmacology 7 (2006) 421-430.
B. Wängler, C. Beck, U. Wagner-Utermann, E. Schirrmacher, C. Bauer, F. Rösch, R. Schirrmacher, M. Eisenhut
Application of tris-allyl-DOTA in the preparation of DOTA-peptide conjugates
Tetrahedron Lett 47 (2006) 5985 – 5988
T. Odenwald, K. Nakagawa, Ch. Hadstein, F. Rösch, P. Gohlke, F. Schaefer, E. Ritz, C.P. Schmitt
Acute blood pressure effects and chronic hypotensive action of calcimimetics in uremic rats
J Am Soc Nephrology 17(3) (2006) 655-62.
U. Baumgärtner, H.-G. Buchholz, A. Bellosevich, W. Magerl, T. Siessmeier, R. Rolke, S. Höhnemann, M. Piel, F. Rösch,
H.-J. Wester, G. Henriksen, P. Stoeter, P. Bartenstein, R.-D.Treede, M. Schreckenberger
High opiate receptor binding potential in the human lateral pain system
Neuroimage 30 (2006) 692-699
M. Jennewein, A. Hermanne, R.P. Mason, P.E. Thorpe, F. Rösch
A new method for the labelling of proteins with radioactive arsenic isotopes
Nucl Instr Methods A 569 (2006) 512-517
H. Uusijärvi, P. Bernhardt, H. Mäcke, F. Rösch, E. Forssell-Aronsson
Electron and positron-emitting radiolanthanides for therapy – A dosimetric and production evaluation
J Nucl Med 47 (2006) 807-814
H. Herzog, F. Rösch
Chemistry and physics of scanners. PET- and SPECT-techniques
Pharm Unserer Zeit 34(6) (2005) 468-73
F. Rösch, G. Gründer, M. Schreckenberger, G. Dannhardt
Radiopharmaceutical strategies and clinical applications. Diagnosis of CNS disease with PET as well as SPECT
Pharm Unserer Zeit 34(6) (2005) 474-82. Erratum in: Pharm Unserer Zeit 35(1) (2006) 7
A.T.J. Klein, F. Rösch, H.H. Coenen, S.M. Qaim
Labelling of manganese-based magnetic resonance imaging (MRI) contrast agents with the positron emitter 51Mn, as exemplified by manganese-tetraphenyl-porphin-sulfonate (MnTPPS4)
Appl Rad Isot 62 (2005) 711-720
U. Mühlhausen, R. Schirrmacher, M. Piel, B. Lecher, G. Nagel, A. Pie-Staffa, B. Kaina, F. Rösch
Synthesis of I-131 labeled glucose-conjugated inhibitors of O6-Methylguanine-DNA Methyltransferase (MGMT) and comparison with non-conjugated inhibitors as potential tools for in vivo MGMT imaging
J Med Chem, 12 (2005) 263-72
S. Schneider, P.J. Feilen, M. Schreckenberger, M. Schwanstecher, C. Schwanstecher, H.-G. Buchholz, O. Thews,
K. Oberholzer, A. Korobeynikov, A. Bauman, S. Comagic, M. Piel, E. Schirrmacher, CY. Shiue, AA. Alavi, P. Bartenstein,
F. Rösch, M.M. Weber, H.H. Klein, R. Schirrmacher
In vitro and in vivo evaluation of novel glibenclamide derivatives as imaging agents for the non-invasive assessment of the pancreatic islet cell mass in animals and humans
Exp Clin Endocrinol Diabetes 7 (2005) 388-395
F. Rösch
Radionuklid-Generatorsysteme für die PET
Der Nuklearmediziner 27 (2004) 226-235
B. Wängler, C. Beck, CY. Shiue, S. Schneider, C. Schwanstecher, M. Schwanstecher, P.J. Feilen, A. Alavi, F. Rösch,
R. Schirrmacher
Synthesis and in vitro evaluation of (S)-2-([11C]methoxy)-4-[3-methyl-1-(2-piperidine-1-yl-phenyl)-butyl-carbamoyl]-benzoic acid ([11C]methoxy-repaglinide): a potential beta-cell imaging agent
Bioorg Med Chem Lett 14/20 (2004) 5205-5209
F. Rösch, E. Forssell-Aronsson
Radio-lanthanides in Nuclear Medicine
in Metal Ions and Their Complexes in Medication (2004) Vol. 42. p. 77-108,
A. Sigel, H. Sigel, Eds. M. Dekker, Inc., New York & Basel
A. Schmitz, CY. Shiue, Q. Feng, GG. Shiue, S. Deng, MT. Pourdehnad, R. Schirrmacher, M. Vatamaniuk, N. Doliba,
F. Matschinsky, B. Wolf, F. Rösch, A. Naji, AA. Alavi
Synthesis and evaluation of fluorine-18 labeled glyburide analogs as beta-cell imaging agents
Nucl Med Biol 31 (2004) 483-491
A. Heinz, T. Siessmeier, J. Wrase, D. Hermann, S. Klein, S.M. Grüsser-Sinopoli, H. Flor, D.F. Braus, H.-G. Buchholz,
G. Gründer, M. Schreckenberger, M. Smolka, F. Rösch, K. Mann, P. Bartenstein
Correlation between dopamine D2 receptors in the ventral striatum and central processing of alcohol cues and craving
Am J Psychiatry 161 (2004) 1783-1789
I. Vernaleken, T. Siessmeier, H.-G. Buchholz, S. Härtter, Ch. Hiemke, P. Stoeter, F. Rösch, P. Bartenstein, G. Gründer
High striatal occupancy of D2-like dopamine receptors by amisulpride in brain of schizophrenic patients: implications for atypical antipsychotic mechanism of action
Int J Neuropsychopharmacol 7/4 (2004) 421-430
B. Kaina, U. Mühlhausen, A. Piee-Staffa, M. Christamnn, R. Garcia Boy, F. Rösch, R. Schirrmacher
Inhibition of O6-methylguanine-DNA methyltransferase (MGMT) by glucose-conjugated inhibitors: Comparison with non-conjugated inhibitors and effect on fotemustine and temolozomide-induced cell death
J Pharmacol Exptl Therap 311 (2004) 585-593.
F. Rösch, E. Forssell-Aronsson
Radio-lanthanides in Nuclear Medicine
in Metal Ions and Their Complexes in Medication (2004) Vol. 42. p. 77-108, A. Sigel, H. Sigel, Eds. M. Dekker,
Inc., New York & Basel.
F. Rösch (ed)
Radiochemistry and Radiopharmaceutical chemistry in Life Sciences
Volume 4 of the Handbook, in A Vértes, S Nagy, Z Klencsár, (eds.), Handbook of Nuclear Chemistry, 2003,
Kluwer Academic Publishers, The Netherlands
F. Rösch, FF. (Russ) Knapp
Radionuclide Generators. In: A Vértes, S Nagy, Z Klencsár, F. Rösch (eds.)
Handbook of Nuclear Chemistry,Vol. 4, pp 81-118, 2003, Kluwer Academic Publishers, The Netherlands
F. Rösch, H.-J. Wester, S. M. Qaim
In memoriam Gerhard Stöcklin.
In: A. Vértes, S. Nagy, Z. Klencsár (eds.), Handbook of Nuclear Chemistry,
Vol. 4, pp xi-xiv, 2003, Kluwer Academic Publishers, Netherlands
H. Hamkens, F. Rösch.
FDG: Biochemical concept and radiochemical synthesis
In: H.-J. Wieler, RE Coleman (eds.), PET in Clinical Oncology, Steinkopff, Darmstadt, 2000, 55-66
F. Rösch
Aktuelle Entwicklungen 18F-markierter onkologischer PET-Tracer
In: HJ Wieler (ed.), PET in der klinischen Onkologie, Steinkopff Verlag, Darmstadt, 1999, 71-84
H. Hamkens, F. Rösch.
FDG: Biochemisches Konzept und radiochemische Synthese
In: H.-J. Wieler (ed.), PET in der klinischen Onkologie, Steinkopff Verlag, Darmstadt, 1999, 59-70
B. Stolz, C. Bruns, R. Albert, F. Rösch, P. Smith-Jones, F. Raulf, D. Hoyer, G. Weckbecker
Somatostatin receptor-targeted radiotherapy – preclinical proof of concept
In: S.W. J. Lamberts (ed), Octreotide: The Next Decade, BioScientifica Ltd. (1999) pp 1-9
E.M. Link, A.S. Michalowski, F. Rösch
211At-Methylene blue for targeted radiotherapy of disseminated melanoma: Microscopic analysis of tumour versus normal tissue damage
Europ J Cancer 32A (1996) 1986-1996
G. Stöcklin, S. M. Qaim, F. Rösch
The impact of radioactivity on life sciences
Radiochim Acta 70/71 (1995) 249-272
E. Schirrmacher, R. Schirrmacher, C. Beck, W. Mier, N. Trautmann, F. Rösch
Synthesis of a Tyr3-octreotate conjugated closo-carborane [HC2B10H10]: a potential compound for boron neutron capture therapy
Tetrahedron Lett 44 (2003) 9143-9145
A. Schildan, R. Schirrmacher, E. Schirrmacher, M. Samochocki, C. Christner, A. Maelicke, F. Rösch
Synthesis and evaluation of tritium labelled 10-methylgalanthamine iodide: A novel compound to examine the mechanism of interaction of galanthamine derivatives with nicotinic acetylcholine receptors
J Label Compd Radiopharm 46 (2003) 1117-1125
R. Schirrmacher, W. Hamkens, F. Rösch
Synthesis of Tritium-labeled (±)-1-[2-(triphenylmethoxy)ethyl]-3-piperidine-carboxylic acid: A possible compound to determine the efficacy of potential GABA transporter substances in vivo
J Lablled Compd Radiopharm 43 (2000) 1127-1134
H. Hamkens, F. Rösch
FDG: Biochemical concept and radiochemical synthesis.
In: HJ Wieler, RE Coleman (eds.), PET in Clinical Oncology, Steinkopff, Darmstadt, 2000, 55-66
J. Brockmann, F. Rösch
Determination of stability constants in Y-DTPA-peptide-systems: Evaluation of a radiochemical method using n.c.a. yttrium-88
Radiochim Acta 87 (1999) 79-85
B. Neumaier, F. Rösch
Ternary Complex Formation of Lanthanides with Phosphate and Serum Proteins in Blood
Radiochim Acta 84 (1999) 201-204
B. Stolz, C. Bruns, R. Albert, F. Rösch, P. Smith-Jones, F. Raulf, D. Hoyer, G. Weckbecker
Somatostatin receptor-targeted radiotherapy – preclinical proof of concept
in: Octreotide: The Next Decade, Ed S W J Lamberts, BioScientifica Ltd. (1999) pp 1-9
J. Brockmann, A. Schmidt, F. Rösch
Radiolabelling of model compounds with [76As]As-arsonic acid and investigation of their stability
J Label Compd Radiopharm 42, suppl. 1 (1999) 759-761
J. Brockmann, A. Schmidt, F. Rösch
Synthesis of carrier-added arsonic acids as precursors for the radiolabelling with arsenic radioisotopes.
J Label Compd Radiopharm 42, suppl. 1 (1999) 303-305
S. Busse, J. Brockmann, F. Rösch
[90Nb]DFO-succinyl-(D)Phe1-octreotide: First radiolabeling experiments of DFO-succinyl-(D)Phe1-octreotide (SDZ 216-927) with analogeous no carrier added 95gNb and investigation of its in vitro stability
J Label Compd Radiopharm 42, suppl. 1 (1999) 300-302
H. Hamkens, F. Rösch
FDG: Biochemisches Konzept und radiochemische Synthese
In: HJ Wieler (ed.), PET in der klinischen Onkologie, Steinkopff Verlag, Darmstadt, 1999, 59-70
B. Neumaier, F. Rösch
Ternary complex formation between yttrium, phosphate and serum proteins: Physicochemical state of yttrium in blood
Radiochim Acta 81 (1998) 171-177
H.J. Wester, J. Brockmann, F. Rösch, B. Stolz, W. Wutz, H. Herzog, P.M. Smith-Jones, C. Bruns, G. Stöcklin
Quantitative in vivo uptake kinetics of 18F-octreotide measured by PET: A comparison with 86Y-DTPA-octreotide and 68Ga-DFO-octreotide in tumor bearing rats
Nucl Med Biol 24 (1997) 275-286
J. Brockmann, F. Rösch, H. Herzog, H. Mühlensiepen, M. Köhle, B. Stolz, P. Marbach, H.W. Müller-Gärtner
Complexation, in vivo-stability, blood clearance and excretion kinetics of 86Y-DOTA-Tyr3-octreotide in baboons
J Label Compd Radiopharm 39 (1997) 468-470
J. Brockmann, F. Rösch
Determination of stability constants in Y-DTPA-peptide systems: Evaluation of a radiochemical method using n.c.a. 88Y
J Label Compd Radiopharm 39 (1997) 471-473
F. Rösch, H. Herzog, C. Plag, B. Neumaier, U. Braun, H.W. Müller-Gärtner, G. Stöcklin
Radiation doses of yttrium-90 citrate and yttrium-90 EDTMP as determined via analogous yttrium-86 complexes and positron emission tomography
Eur J Nucl Med 23 (1996) 958-966
E.M Link, A.S. Michalowski, F. Rösch
211At-Methylene blue for targeted radiotherapy of disseminated melanoma: Microscopic analysis of tumour versus normal tissue damage
Europ J Cancer 32A (1996) 1986-1996
B. Neumaier, F. Rösch
Binding of radioyttrium to human serum albumin: Relevance to endotherapeutic applications of 90Y-labelled pharmaceutics
J Label Compd Radiopharm 37 (1995) 569-570
J. Brockmann, F. Rösch
Labelling of small peptides with yttrium and gallium via a new DOTA-derivative or DFO using different disuccinimidylic esters as linker
J Label Compd Radiopharm 37 (1995) 516-518
J. Brockmann, F. Rösch, H. Herzog, B. Stolz, C. Bruns, G. Stöcklin
In vivo uptake kinetics and dosimetric calculations of 56Y-DTPA-octreotide with PET as a model for potential endotherapeutic octreotides labeled with 90Y
J Label Compd Radiopharm 37 (1995) 519-521
G. Stöcklin, S.M. Qaim, F. Rösch
The impact of radioactivity on life sciences
Radiochim Acta 70/71 (1995) 249-272
H. Herzog, F. Rösch, G. Stöcklin, C. Lueders, S.M. Qaim, L.E. Feinendegen
Measurement of pharmacokinetics of yttrium-86 radiopharmaceuticals with PET and radiation dose calculation of analogous yttrium-90 radiotherapeutics
J Nucl Med 34 (1993) 2222-2226
G.J. Beyer, R. Bergmann, G. Kampf, P. Mäding, F. Rösch
Simultaneous study of the biodistribution of radio-yttrium complexed with EDTMP and citrate ligands in tumour-bearing rats
Nucl Med Biol 19 / 2/ (1992) 201-203
P. Mäding, J. Römer, F. Rösch
Chemical synthesis of L-[75Se]selenomethionine in a high-activity scale
Int J Appl Radiat Isot 43 /4/ (1992) 495-501
F. Rösch, T. Brankoff, H. Görner, B. Große, K.-H. Kasper, C. Kretzschmar, P. Mäding, E. Mittag, S. Noll, D. Poser,
K. Rockstroh, J. Römer, G. Ryssel, G. Schäfer
Chemische Synthese von L-[75Se]Selenomethionin für die Routineproduktion
Report ZfK-737 (1991)
F. Rösch, G.J. Beyer
Längerlebige Positron-Emitter: Einzelnuklide und Generatorsysteme, Herstellung am U-120 Zyklotron in Rossendorf, radiochemische Studien sowie Möglichkeiten für die PET
Report ZfK-771 (1991)
G.J. Beyer, R. Bergmann, K. Schomäcker, F. Rösch, G. Schäfer, EV. Kulikov, AF. Novgorodov
Comparison of the Biodistribution of 225Ac and Radiolanthanides as Citrate Complexes
Isotopenpraxis 26 /3/ (1990) 111-114
G. Wunderlich, E. Henke, F. Rösch, W.-G. Franke, R. Dreyer
Tierexperimentelle Studien zur Biokinetik von Astatid und Astat(I)-Komplexverbindungen
Radiobiol Radiotherap 27 /4/ (1986) 387-392
R. Dreyer, I. Dreyer, W. Doberenz, S. Fischer, VA. Khalkin, F. Rösch
Zur anorganischen Chemie des monovalenten Astats
Isotopenpraxis 22 /3/ (1986) 81-87
R. Dreyer, I. Dreyer, S. Fischer, H. Hartmann, F. Rösch
Syntheses and characterization of cationic astatine compounds with sulfur-containing ligands stable in aqueous solution
J Radioanal Nucl Chem 96 /3/ (1985) 387-392
R. Dreyer, I. Dreyer, F. Rösch, S. Fischer
Synthesen und erste Charakterisierung von in wässrigen Lösungen stabilen Verbindungen des At(*)+ mit Thioharnstoff und Thioharnstoffderivaten
Z Chem 23 /9/ (1983) 346-347
R. Dreyer, I. Dreyer, F. Rösch, G.J. Beyer
Studies of polyhalogenide ions of astatine
Radiochem Radioanal Lett 54 /3/ (1982) 165-176
R. Dreyer, I. Dreyer, F. Rösch
Zum Verhalten des Astatids in Halogenidlösungen
Z Chem 22 /2/ (1982) 54-55
R. Dreyer, F. Rösch, G.J. Beyer
Astat - Erforschung eines Unbeständigen
Wissenschaft und Fortschritt 32 (1982) 251-255
R. Dreyer, I. Dreyer, M. Pfeiffer, F. Rösch
Pseudohalogen compounds of astatine
First Syntheses and Characterizations of At-Rhodanide and At-Cyanide Compounds Radiochem Radioanal Lett 55 /4/ (1982) 207-214
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